anti- CD4 antibody

Dive into the world of immune modulation and T cell research with our Anti-CD4 Polyclonal Antibody, now available in a convenient 100µg size. CD4, a cell surface glycoprotein predominantly expressed on helper T cells, is a key player in immune responses, orchestrating T cell activation and interaction with antigen-presenting cells.

Our meticulously developed polyclonal antibody, derived from rabbit hosts, offers exceptional sensitivity and versatility for various research applications. Whether you're studying CD4-mediated immune modulation or investigating its role in immunotherapy, this antibody's polyclonal nature allows recognition of multiple epitopes, enhancing its utility in diverse research contexts.

With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the intricate mechanisms by which CD4 influences T cell activation, differentiation, and its pivotal role in adaptive immune responses. Investigate the molecular intricacies of CD4-mediated processes, contributing to our understanding of immunological disorders and potential therapeutic interventions.

Product Name

CD4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

IMMUNOGEN INFORMATION

Immunogen

CD4 molecule

Synonyms

CD4, CD4 molecule, CD4mut,T-cell surface glycoprotein CD4,T-cell surface antigen T4/Leu-3

Observed MW

51 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P01730

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