anti- CD41/Integrin alpha 2b antibody

Embark on a journey into the world of platelet biology and hemostasis with our Anti-CD41 (Integrin alpha 2b) Antibody, now available in a convenient 100µg size. CD41, also known as integrin alpha 2b, is a critical component of the platelet fibrinogen receptor complex, facilitating platelet aggregation and clot formation.

Our meticulously developed monoclonal antibody offers exceptional specificity and sensitivity for researchers investigating platelet function and thrombosis. With 100µg at your disposal, you have a generous supply for multiple experiments, reducing the need for frequent reordering and ensuring the continuity of your research.

Explore the intricate mechanisms underlying CD41-mediated platelet aggregation, adhesion, and its pivotal role in hemostasis and thrombosis. Investigate the molecular interactions that govern platelet biology, contributing to our understanding of clotting disorders and potential therapeutic interventions.

Product Name

CD41/Integrin alpha 2b antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands(PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits(PMID: 17543136; 20029421).

IMMUNOGEN INFORMATION

Immunogen

integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Synonyms

CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB

Observed MW

125 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:1000-1:10000
IP:1:1000-1:10000
IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P08514

IMAGES