anti- CD47 antibody

Embark on a journey into the intricate world of immune checkpoint biology and cancer research with our Anti-CD47 Antibody, available in a 100µg size. CD47 is a pivotal surface molecule involved in immune evasion, and this monoclonal antibody offers exceptional specificity for precise targeting in your experiments.

Whether you're conducting immunohistochemistry, flow cytometry, or functional assays, this antibody provides the consistency and accuracy you need. It is an indispensable tool for advancing your understanding of CD47-mediated immune responses and its role in cancer immunotherapy.

Trust in the quality of our Anti-CD47 Antibody to drive your research forward and contribute to a better understanding of immune checkpoint blockade and its potential in cancer treatment. Stay at the forefront of scientific discovery with this essential reagent.

Product Name

CD47 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus(By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

IMMUNOGEN INFORMATION

Immunogen

CD47 molecule

Synonyms

CD47, CD47 molecule, IAP, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6

Observed MW

47-55 kDa

APPLICATION

Tested Application

ELISA, WB,IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q08722

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