anti- CD59 antibody

Uncover the secrets of complement regulation and cell membrane protection with our Anti-CD59 Antibody, available in a 100µg size. CD59 is a crucial player in inhibiting the formation of the membrane attack complex, and this monoclonal antibody offers exceptional specificity for precise targeting in your experiments.

Whether you're involved in immunohistochemistry, flow cytometry, or Western blotting, this antibody provides the consistency and accuracy you need. It is an indispensable tool for advancing your understanding of CD59-mediated complement regulation and its implications in various diseases.

Trust in the quality of our Anti-CD59 Antibody to drive your research forward and contribute to a better understanding of immune responses and membrane protection mechanisms. Stay at the forefront of scientific discovery with this essential reagent.

Product Name

CD59 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

IMMUNOGEN INFORMATION

Immunogen

CD59 molecule, complement regulatory protein

Synonyms

MIC11, MIN1, MIN2, MIN3, MSK21

Observed MW

18-20 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P13987

IMAGES