1 1

FineTest

FNab01504

anti- CD86 antibody

anti- CD86 antibody

$290.00 USD
$290.00 USD
Sale Sold out
Shipping calculated at checkout.
size

Explore the complexities of immune co-stimulation and antigen-presenting cell activation with our Anti-CD86 Antibody, available in a 100µg size. CD86, also known as B7-2, is a critical co-stimulatory molecule involved in regulating immune responses and antigen presentation.

Whether you're conducting flow cytometry, immunohistochemistry, or functional assays, this highly specific monoclonal antibody delivers consistent and dependable results. It is an indispensable tool for advancing your understanding of CD86-mediated immune co-stimulation and its implications in autoimmunity and cancer immunotherapy.

Trust in the quality and performance of our Anti-CD86 Antibody to drive your research forward and contribute to a better understanding of immune co-stimulation and immune checkpoint blockade. Stay at the forefront of scientific discovery with this essential reagent.

Product Name

CD86 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.

IMMUNOGEN INFORMATION

Immunogen

CD86 molecule

Synonyms

Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72

Observed MW

75 kDa

APPLICATION

Tested Application

ELISA, WB,IHC,IF

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P42081

IMAGES

 

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01504(CD86 Antibody) at dilution of 1:200. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunofluorescent analysis of RAW264.7 cells using FNab01504 ( CD86 Antibody) at dilution of 1:50.
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01504(CD86 antibody) at dilution of 1:500

 

View full details