anti- CDC25B antibody

Delve into the intricacies of cell cycle control and phosphatase regulation with our Anti-CDC25B Antibody, available in a 100µg size. CDC25B, a key member of the CDC25 phosphatase family, plays a critical role in activating cyclin-dependent kinases (CDKs) and promoting cell cycle progression.

Whether you're conducting immunoprecipitation, immunohistochemistry, or functional assays, this highly specific monoclonal antibody delivers consistent and dependable results. It is an indispensable tool for advancing your understanding of CDC25B-mediated cell cycle control and its implications in cancer biology and genome stability.

Trust in the quality and performance of our Anti-CDC25B Antibody to drive your research forward and contribute to a better understanding of cell cycle checkpoints and cell division.

Product Name

CDC25B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CDC25B, also named as CDC25HU2, belongs to the MPI phosphatase family. It is a tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. CDC25B directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. In Jurkat cell, this antibody recognized 2 bands: 60kd(isoform 2, CDC25B2) and 70kd(isoform 4 of CDC25B).

IMMUNOGEN INFORMATION

Immunogen

cell division cycle 25 homolog B(S. pombe)

Synonyms

CDC25B, CDC25HU2, M phase inducer phosphatase 2

Observed MW

60-70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P30305

IMAGES