anti- CDC42 antibody

Unravel the mysteries of cellular signaling pathways with our Anti-CDC42 Antibody, now available in a 100µg size. CDC42, or cell division cycle 42, is a small GTPase that plays a central role in regulating cellular processes such as cytoskeletal dynamics, cell migration, and cell polarity.

This monoclonal antibody offers exceptional specificity and sensitivity, making it an indispensable tool for researchers investigating cell signaling, cytoskeletal reorganization, and the molecular mechanisms governing cell behavior. With 100µg of this antibody, you'll have a substantial supply for various experiments, ensuring the continuity of your research.

Explore the intricate role of CDC42 in cellular signaling pathways, its interactions with downstream effectors, and its potential implications in processes such as cell adhesion, motility, and cancer metastasis.

Product Name

CDC42 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.

IMMUNOGEN INFORMATION

Immunogen

cell division cycle 42 (GTP binding protein, 25kDa)

Synonyms

CDC42Hs, G25K, TKS

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P60953

IMAGES