anti- CDCA2 antibody

Delve into the intricacies of cell cycle regulation and DNA replication with our Anti-CDCA2 Antibody, now available in a 100µg size. CDCA2, or cell division cycle-associated 2, is a critical player in DNA replication licensing and is essential for proper cell cycle progression.

This monoclonal antibody offers high specificity and sensitivity, making it an invaluable tool for researchers investigating cell cycle checkpoints, DNA replication, and the molecular mechanisms governing cell proliferation. With 100µg of this antibody, you'll have an ample supply for multiple experiments, ensuring the continuity of your research.

Unravel the complexities of CDCA2 and its role in DNA replication initiation. Investigate its interactions with other licensing factors and its potential implications in cancer therapy, genomic stability, and developmental biology.

Product Name

CDCA2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit(PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.

IMMUNOGEN INFORMATION

Immunogen

cell division cycle associated 2

Synonyms

CDCA2, Repo Man

Observed MW

125 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q69YH5

IMAGES

Immunohistochemistry of paraffin-embedded human gastric carcinoma tissue slide using FNab01539(CDCA2 Antibody) at dilution of 1:100.Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min.

IP Result of anti-CDCA2 (IP:FNab01539, 4ug; Detection:FNab01539 1:800) with Jurkat cells lysate 2800ug.

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01539(CDCA2 antibody) at dilution of 1:500