anti- CDCA8 antibody

Delve into the intricate world of cell division and chromosome segregation with our Anti-CDCA8 Antibody, now available in a 100µg size. CDCA8, or cell division cycle-associated 8, is a key component of the chromosomal passenger complex (CPC), essential for accurate chromosome alignment and segregation during mitosis.

Our meticulously developed monoclonal antibody offers exceptional sensitivity and specificity, making it an indispensable tool for researchers investigating cell cycle regulation, mitosis, and the molecular mechanisms governing chromosome segregation. With 100µg of this antibody, you'll have an ample supply for multiple experiments, ensuring the continuity of your research.

Unlock the secrets of CDCA8 and its significance in orchestrating the events of mitosis. Investigate its interactions with other CPC components and its potential implications in cancer biology, genomic stability, and therapeutic interventions.

Product Name

CDCA8 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the chromosomal passenger complex(CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

IMMUNOGEN INFORMATION

Immunogen

cell division cycle associated 8

Synonyms

PESCRG3

Observed MW

38-40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q53HL2

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab01544(CDCA8 antibody) at dilution of 1:50

mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01544(CDCA8 antibody) at dilution of 1:300