anti- CDK3 antibody

Delve into the intricacies of cell cycle regulation with our Anti-CDK3 Antibody, now available in a 100µg size. Cyclin-dependent kinase 3 (CDK3) is a less studied member of the CDK family, making it an intriguing target for researchers exploring cell cycle control and its role in cellular processes.

This monoclonal antibody offers remarkable specificity and sensitivity, making it an invaluable tool for researchers investigating cell cycle dynamics, cellular growth, and the molecular mechanisms underlying CDK3 function. With 100µg of this antibody, you'll have a substantial supply for various experiments, ensuring the continuity of your research.

Uncover the mysteries of CDK3 and its significance in cell cycle checkpoints, its potential interactions with unique cyclins, and its implications in cell biology, cancer research, and targeted therapies.

Product Name

CDK3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

IMMUNOGEN INFORMATION

Immunogen

cyclin-dependent kinase 3

Synonyms

CDKN3

Observed MW

40-45 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q00526

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