anti- CENPC antibody

Unlock the mysteries of centromere organization and chromosome segregation with our Anti-CENPC Antibody, now available in a 100µg size. CENPC, or centromere protein C, is a central player in centromere structure, ensuring proper kinetochore assembly and chromosome attachment during cell division. This monoclonal antibody offers exceptional specificity and sensitivity, making it an indispensable tool for researchers exploring cell cycle regulation, mitosis, and the molecular mechanisms governing centromere integrity.

With 100µg of this antibody, you'll have an ample supply for various experiments, ensuring the continuity of your research. Investigate the complexities of CENPC and its role in kinetochore formation, its interactions with other centromeric proteins, and its potential implications in cancer biology, chromosome instability, and therapeutic interventions.

Product Name

CENPC antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.

IMMUNOGEN INFORMATION

Immunogen

centromere protein C 1

Synonyms

CENPC1, ICEN7

Observed MW

130 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q03188

IMAGES

Immunohistochemistry of paraffin-embedded human kidney cancer using FNab01584(CENPC antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab01584(CENPC antibody) at dilution of 1:1000