anti- CENPN antibody

Dive into the intricate world of centromeres with our Anti-CENPN Antibody, an invaluable tool for cell biologists and geneticists. This antibody is specifically designed to target Centromere Protein N (CENPN), a critical component of the centromere complex that ensures accurate chromosome segregation during cell division. With a generous 100µg size, you'll have an ample supply for your experiments.

CENPN is a central player in maintaining genomic stability and is a focus of research in cell biology and genetics. Our antibody undergoes rigorous testing to guarantee specificity and sensitivity, providing you with dependable results. Whether you're investigating mitosis, meiosis, or other related processes, our Anti-CENPN Antibody is your go-to research tool.

This product is versatile, suitable for applications such as Western blotting, immunofluorescence, and chromatin immunoprecipitation (ChIP). Its high purity and specificity reduce background noise, enhancing the accuracy of your experiments. Uncover the secrets of centromere biology with confidence, equipped with our Anti-CENPN Antibody.

Product Name

CENPN antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.

IMMUNOGEN INFORMATION

Immunogen

centromere protein N

Synonyms

C16orf60, ICEN32

Observed MW

40 kDa, 25-30 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q96H22

IMAGES

MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab01589(CENPN Antibody) at dilution of 1:1000