anti- CEP152 antibody

Introducing our Anti-CEP152 Antibody, a cutting-edge tool for researchers in the field of cell biology and genetics. This high-quality antibody is designed to target Centrosomal Protein 152 (CEP152), a crucial protein involved in centrosome function and cell division regulation. With a generous 100µg size, this product offers ample quantities for your experiments.

CEP152 plays a pivotal role in centrosome duplication and maturation, making it a key player in maintaining genomic stability. Our antibody is rigorously tested to ensure specificity and sensitivity, guaranteeing reliable results in your experiments. Whether you are investigating cell cycle control, centrosome biology, or related pathways, our Anti-CEP152 Antibody is your trusted partner.

This product is suitable for various applications, including Western blotting, immunofluorescence, and immunoprecipitation. Its high purity and specificity ensure minimal background noise, enhancing the accuracy of your results. Unlock the secrets of centrosome biology with confidence, using our Anti-CEP152 Antibody.

Product Name

CEP152 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Necessary for centrosome duplication; the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication(PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation(PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure(PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles(By similarity). Overexpression of CEP152 can drive amplification of centrioles(PubMed:20852615).

IMMUNOGEN INFORMATION

Immunogen

centrosomal protein 152kDa

Synonyms

KIAA0912

Observed MW

110 kDa

APPLICATION

Tested Application

ELISA, IP, WB

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

UNIPROT INFORMATION

UniProt ID

O94986

IMAGES

IP Result of anti-CEP152 (IP:FNab01597, 3ug; Detection:FNab01597 1:500) with mouse brain tissue lysate 9500ug.

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01597( CEP152 Antibody) at dilution of 1:300