anti- CES1 antibody

Elevate your research with our Anti-CES1 Antibody, designed to provide accurate and reproducible results for your experiments. CES1, or carboxylesterase 1, is a critical enzyme involved in the hydrolysis of ester and amide bonds in various compounds, making it an essential focus in drug metabolism and xenobiotic detoxification research.

Our polyclonal Anti-CES1 Antibody is available in a 100µg size, ensuring you have an adequate supply for multiple experiments across various applications, including Western blotting and immunohistochemistry. Rigorously validated for specificity and sensitivity, this antibody will help you uncover the intricacies of CES1 expression and function.

CES1 is implicated in the metabolism of a wide range of drugs, and its activity can significantly affect drug efficacy and toxicity. By utilizing our Anti-CES1 Antibody, you can gain deeper insights into drug metabolism pathways, potentially leading to the development of safer and more effective pharmaceuticals.

Advance your research with confidence by choosing our Anti-CES1 Antibody. With its reliability and precision, it's the perfect tool to unravel the mysteries of drug metabolism and xenobiotic detoxification mechanisms.

Product Name

CES1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Synonyms

CES2, SES1

Observed MW

62 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P23141

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer using FNab01615(CES1 antibody) at dilution of 1:100

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01615(CES1 antibody) at dilution of 1:1000