anti- CES2 antibody

Uncover the potential of your research with our high-quality Anti-CES2 Antibody. CES2, also known as carboxylesterase 2, is a critical enzyme involved in drug metabolism and hydrolysis of various ester compounds. This polyclonal antibody, provided in a 100µg size, is the perfect tool to investigate CES2 expression and function in your experiments.

Our Anti-CES2 Antibody is rigorously validated to ensure specificity and sensitivity, making it ideal for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its 100µg quantity ensures you have an ample supply for multiple experiments.

CES2 plays a pivotal role in drug metabolism, particularly in the activation and inactivation of prodrugs, making it a key target in pharmaceutical research. By using our Anti-CES2 Antibody, you can gain valuable insights into drug metabolism pathways, ultimately contributing to the development of safer and more effective therapeutics.

Trust in the quality of our antibodies to advance your research. With its precision and reliability, our Anti-CES2 Antibody will help you unlock new discoveries in the field of drug metabolism and beyond.

Product Name

CES2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

carboxylesterase 2 (intestine, liver)

Synonyms

CE-2;CES2A1;PCE-2;iCE

Observed MW

62kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O00748

IMAGES

Immunohistochemistry of paraffin-embedded human colon cancer using FNab01616(CES2 antibody) at dilution of 1:100

SW620 cells were subjected to SDS PAGE followed by western blot with FNab01616(CES2 antibody) at dilution of 1:1000