anti- CHAF1A antibody

Delve into the intricacies of chromatin biology with our Anti-CHAF1A Antibody, available in a 100µg size. Chromatin Assembly Factor 1, subunit A (CHAF1A), is a critical player in DNA replication and chromatin assembly, ensuring faithful transmission of genetic information.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CHAF1A protein in your experiments. Researchers studying DNA replication, epigenetics, or related areas will benefit from the precision and reliability of this antibody.

Our Anti-CHAF1A Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Take your research on DNA replication and chromatin structure to the next level with this essential tool.

Product Name

CHAF1A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci(By similarity).

IMMUNOGEN INFORMATION

Immunogen

chromatin assembly factor 1, subunit A(p150)

Synonyms

CAF, CAF1P150

Observed MW

150 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IP, IF

Recommended Dilution

WB: 1:1000-1:4000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q13111

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