anti- CHI3L1 antibody

Delve into the world of inflammation and disease biomarkers with our Anti-CHI3L1 Antibody, available in a 100µg size. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a key player in inflammation, tissue remodeling, and cancer progression.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CHI3L1 protein in your experiments. Researchers studying inflammatory diseases, cancer biology, or related fields will appreciate the precision and reliability of this antibody.

Our Anti-CHI3L1 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Join the forefront of biomarker research and gain valuable insights into the role of CHI3L1 in health and disease.

Product Name

CHI3L1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2(Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

IMMUNOGEN INFORMATION

Immunogen

chitinase 3-like 1(cartilage glycoprotein-39)

Synonyms

39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP 39, CHI3L1, Chitinase 3 like protein 1, GP 39, GP39, HC gp39, hCGP 39, HCGP 3P, YKL 40, YKL40, YYL 40

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P36222

IMAGES