anti- Chk1 antibody

Embark on a journey into the intricate world of cell cycle regulation and DNA damage response with our Anti-Chk1 Antibody, available in a 100µg size. Checkpoint kinase 1 (Chk1) is a key player in the DNA damage checkpoint pathway, orchestrating cell cycle arrest and DNA repair.

This meticulously designed polyclonal antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of Chk1 protein in your experiments. Researchers studying cell cycle progression, DNA replication, or related areas will benefit from the precision and reliability of this antibody.

Our Anti-Chk1 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Take your research on cell cycle regulation and DNA damage response to the next level with this essential tool.

Product Name

Chk1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

HEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa.

IMMUNOGEN INFORMATION

Immunogen

CHK1 checkpoint homolog

Synonyms

CHEK1, Chk1

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14757

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