anti- CHST1 antibody

Uncover the intricacies of glycosaminoglycan biosynthesis with our Anti-CHST1 Antibody, available in a 100µg size. Carbohydrate Sulfotransferase 1 (CHST1), also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase 1, is a pivotal enzyme involved in the sulfation of carbohydrate chains, a critical step in the formation of proteoglycans.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CHST1 protein in your experiments. Researchers studying glycobiology, matrix biology, or related areas will benefit from the precision and reliability of this antibody.

Our Anti-CHST1 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Take your research on proteoglycan synthesis and extracellular matrix dynamics to the next level with this essential tool.

Product Name

CHST1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate(PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose(Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells(HEVs) and play a central role in lymphocyte homing at sites of inflammation.

IMMUNOGEN INFORMATION

Immunogen

carbohydrate(keratan sulfate Gal-6) sulfotransferase 1

Observed MW

48-55 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O43916

IMAGES

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01689(CHST1 antibody) at dilution of 1:500