anti- CHST14 antibody

Embark on a journey into the world of glycosaminoglycan biosynthesis with our Anti-CHST14 Antibody, available in a 100µg size. Carbohydrate Sulfotransferase 14 (CHST14), also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase 5, is a critical enzyme involved in the sulfation of carbohydrate chains, essential for the formation of proteoglycans.

This high-quality antibody is meticulously designed to provide exceptional specificity and sensitivity, ensuring accurate detection of CHST14 protein in your experiments. Researchers studying glycobiology, extracellular matrix dynamics, or related areas will appreciate the precision and reliability of this antibody.

Our Anti-CHST14 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Join the forefront of research into proteoglycan synthesis and gain valuable insights into the role of CHST14 in modulating tissue development and matrix properties.

Product Name

CHST14 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.

IMMUNOGEN INFORMATION

Immunogen

carbohydrate(N-acetylgalactosamine 4-0) sulfotransferase 14

Synonyms

D4ST1

Observed MW

45-50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8NCH0

IMAGES

Immunohistochemistry of paraffin-embedded human placenta using FNab01694(CHST14 antibody) at dilution of 1:50

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01694(CHST14 antibody) at dilution of 1:600