anti- CIDEA antibody

Dive into the world of metabolic regulation and lipid metabolism with our Anti-CIDEA Antibody, available in a 100µg size. Cell Death-Inducing DFFA-Like Effector A (CIDEA) is a crucial protein involved in the regulation of lipid droplet formation and energy expenditure.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CIDEA protein in your experiments. Researchers studying obesity, lipid homeostasis, or related areas will appreciate the precision and reliability of this antibody.

Our Anti-CIDEA Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Join the forefront of metabolic research and gain valuable insights into the role of CIDEA in adipocyte biology and energy balance.

Product Name

CIDEA antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter(By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

IMMUNOGEN INFORMATION

Immunogen

cell death-inducing DFFA-like effector a

Observed MW

25kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O60543

IMAGES

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab01710(CIDEA antibody) at dilution of 1:1000