anti- CISD2 antibody

Explore the realm of mitochondrial function and cellular homeostasis with our Anti-CISD2 Antibody, available in a 100µg size. CDGSH Iron-Sulfur Domain 2 (CISD2), also known as Miner1, is a pivotal protein involved in maintaining mitochondrial iron homeostasis and protecting cells from oxidative stress.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CISD2 protein in your experiments. Researchers studying mitochondrial biology, iron metabolism, or related areas will appreciate the precision and reliability of this antibody.

Our Anti-CISD2 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Join the forefront of research into mitochondrial function and gain valuable insights into the role of CISD2 in cellular health and iron handling.

Product Name

CISD2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

IMMUNOGEN INFORMATION

Immunogen

CDGSH iron sulfur domain 2

Synonyms

CDGSH2, ERIS, ZCD2

Observed MW

13-15 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8N5K1

IMAGES

Immunohistochemistry of paraffin-embedded human kidney using FNab01718(CISD2 antibody) at dilution of 1:100

IP Result of anti-CISD2 (IP:FNab01718, 3ug; Detection:FNab01718 1:700) with mouse brain tissue lysate 4000ug.

mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01718(CISD2 antibody) at dilution of 1:1000