anti- CKMT2 antibody

Unlock the secrets of mitochondrial function with our Anti-CKMT2 Antibody, now available in a 100µg size. CKMT2 (Creatine Kinase Mitochondrial 2) is a crucial enzyme found in the mitochondria, where it plays a vital role in energy metabolism and the generation of cellular ATP.

Our meticulously designed antibody offers exceptional specificity and sensitivity, ensuring precise detection of CKMT2 protein in your experiments. Researchers investigating mitochondrial bioenergetics, cellular respiration, or related areas will appreciate the accuracy and reliability of this antibody.

This high-quality Anti-CKMT2 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of research into mitochondrial function and gain valuable insights into the role of CKMT2 in cellular energy production.

Product Name

CKMT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

creatine kinase, mitochondrial 2 (sarcomeric)

Observed MW

48 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

UNIPROT INFORMATION

UniProt ID

P17540

IMAGES

Immunohistochemistry of paraffin-embedded mouse heart using FNab01728( CKMT2 Antibody) at dilution of 1:50

human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab01728(CKMT2 antibody) at dilution of 1:1000