anti- Claudin 3 antibody

Uncover the intricacies of cell-cell junctions and epithelial barrier function with our Anti-Claudin 3 Antibody, available in a 100µg size. Claudin 3 is a key component of tight junctions, contributing to the formation of impermeable barriers in epithelial and endothelial tissues.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of Claudin 3 protein in your experiments. Researchers studying epithelial biology, barrier function, or related areas will appreciate the precision and reliability of this antibody.

Our Anti-Claudin 3 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of research into tight junction dynamics and gain valuable insights into the role of Claudin 3 in tissue integrity.

Product Name

Claudin 3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

IMMUNOGEN INFORMATION

Immunogen

claudin 3

Synonyms

C7orf1, claudin 3, Claudin3, CLDN3, CPE R 2, CPE R2, CPE receptor 2, CPETR2, HRVP1, RVP1

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

O15551

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01738( Claudin 3 Antibody) at dilution of 1:100

mouse colon tissue were subjected to SDS PAGE followed by western blot with FNab01738( Claudin 3 Antibody) at dilution of 1:1000