anti- Claudin 4-specific antibody

Delve into the intricate world of tight junctions and epithelial barrier function with our Anti-Claudin 4-Specific Antibody, now available in a 100µg size. Claudin 4 is a critical component of tight junctions in epithelial cells, contributing to the formation and maintenance of epithelial barriers.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of Claudin 4 protein in your experiments. Researchers studying epithelial biology, barrier function, or related areas will benefit from the accuracy and reliability of this antibody.

Our high-quality Anti-Claudin 4-Specific Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of epithelial barrier research and gain valuable insights into the role of Claudin 4 in regulating epithelial permeability and barrier integrity.

Product Name

Claudin 4-specific antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small(20-27 kDa) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. This antibody is specifically against claudin 4.

IMMUNOGEN INFORMATION

Immunogen

claudin 4

Synonyms

claudin 4, CLDN4, CPE R, CPE receptor, CPER, CPETR, CPETR1, hCPE R, WBSCR8

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14493

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab01739(Claudin 4-specific Antibody) at dilution of 1:50

IP Result of anti-Claudin 4-specific (IP:FNab01739, 4ug; Detection:FNab01739 1:300) with human placenta tissue lysate 4400ug.

mouse small intestine tissue were subjected to SDS PAGE followed by western blot with FNab01739(CLDN4-specific antibody) at dilution of 1:500