anti- CLEC4M antibody

Delve into the intriguing world of C-type lectin receptors and immune signaling with our Anti-CLEC4M Antibody, now available in a 100µg size. CLEC4M (C-type Lectin Domain Family 4 Member M), also known as L-SIGN (Liver/Lymph Node-Specific ICAM-3-Grabbing Non-Integrin), is involved in pathogen recognition and immune responses.

This meticulously designed antibody offers exceptional specificity and sensitivity, ensuring accurate detection of CLEC4M protein in your experiments. Researchers investigating immune cell interactions, pathogen recognition, or related areas will appreciate the precision and reliability of this antibody.

Our high-quality Anti-CLEC4M Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of immune receptor research and gain valuable insights into the role of CLEC4M in mediating host-pathogen interactions.

Product Name

CLEC4M antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus(PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus(PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1(PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E(PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5(PubMed:12433371). Acts as an attachment receptor for influenzavirus(PubMed:21191006). Acts as an attachment receptor for SARS coronavirus(PubMed:15479853). Acts as an attachment receptor for west-nile virus(PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus(PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein(PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule(PubMed:21203928).

IMMUNOGEN INFORMATION

Immunogen

C-type lectin domain family 4, member M

Synonyms

CD209L, CD209L1, CD299

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9H2X3

IMAGES

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01757(CLEC4M Antibody) at dilution of 1:50

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01757(CLEC4M Antibody) at dilution of 1:3000