anti- CLK2 antibody

Embark on a journey into the world of kinase signaling and circadian rhythms with our Anti-CLK2 Antibody, available in a 100µg size. CLK2 (Cdc2-Like Kinase 2) is a key regulator of circadian clock function and contributes to the control of various cellular processes.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring precise detection of CLK2 protein in your experiments. Researchers studying circadian biology, kinase signaling, or related areas will appreciate the accuracy and reliability of this antibody.

Our high-quality Anti-CLK2 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of circadian rhythm research and gain valuable insights into the role of CLK2 in coordinating biological processes with the day-night cycle.

Product Name

CLK2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine-and arginine-rich(SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor(F3) pre-mRNA in endothelial cells.

IMMUNOGEN INFORMATION

Immunogen

CDC-like kinase 2

APPLICATION

Tested Application

ELISA

UNIPROT INFORMATION

UniProt ID

P49760