anti- CLPP antibody

Delve into the fascinating world of mitochondrial protein quality control with our Anti-CLPP Antibody, available in a 100µg size. CLPP (Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit) is a critical component of the mitochondrial protease complex responsible for maintaining mitochondrial protein homeostasis.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring precise detection of CLPP protein in your experiments. Researchers investigating mitochondrial biology, protein degradation, or related areas will appreciate the accuracy and reliability of this antibody.

Our high-quality Anti-CLPP Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Dive into the forefront of mitochondrial research and gain valuable insights into the role of CLPP in maintaining mitochondrial function and cellular health.

Product Name

CLPP antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides(in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.

IMMUNOGEN INFORMATION

Immunogen

ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog

Synonyms

CLPP, Endopeptidase Clp

Observed MW

26 kDa, 30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:5000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q16740

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab01772(CLPP Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Immunofluorescent analysis of Hela cells using CLPP antibody FNab01772 at 1:25 dulution

IP Result of anti-CLPP(IP: FNab01772, 3μg; Detection: FNab01772, 1:500) with mouse skeletal muscle tissue lysate 3000μg

K-562 cells were subjected to SDS PAGE followed by western blot with FNab01772(CLPP antibody) at dilution of 1:500