anti- CLSTN1 antibody

Delve into the intriguing world of synaptic adhesion and neuronal function with our Anti-CLSTN1 Antibody, now available in a 100µg size. CLSTN1 (Calsyntenin 1), also known as Alcadein alpha, plays a critical role in synapse formation and axonal transport.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring precise detection of CLSTN1 protein in your experiments. Researchers investigating synaptic plasticity, neuronal development, or related areas will appreciate the precision and reliability of this antibody.

Our high-quality Anti-CLSTN1 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Dive into the forefront of synaptic adhesion research and gain valuable insights into the role of CLSTN1 in neuronal connectivity and function.

Product Name

CLSTN1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment(AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals(By similarity).

IMMUNOGEN INFORMATION

Immunogen

calsyntenin 1

Synonyms

CS1, KIAA0911

Observed MW

109kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O94985

IMAGES

human brain tissue were subjected to SDS PAGE followed by western blot with FNab01776(CLSTN1 antibody) at dilution of 1:600