anti- Clusterin antibody

Explore the versatile world of extracellular chaperone proteins and cell-cell interactions with our Anti-Clusterin Antibody, now available in a 100µg size. Clusterin, also known as Apolipoprotein J, is a multifunctional glycoprotein implicated in various physiological processes, including cell adhesion, tissue remodeling, and immune response regulation.

This meticulously designed antibody offers exceptional specificity and sensitivity, ensuring accurate detection of Clusterin protein in your experiments. Researchers investigating extracellular matrix dynamics, cell signaling, or related areas will appreciate the precision and reliability of this antibody.

Our high-quality Anti-Clusterin Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Dive into the forefront of extracellular protein research and gain valuable insights into the multifaceted role of Clusterin in modulating cell behavior and tissue homeostasis.

Product Name

Clusterin antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into α (34-36 kDa) and β (36-39 kDa) subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).

IMMUNOGEN INFORMATION

Immunogen

clusterin

Synonyms

AAG4, Apo J, APOJ, ApoJalpha, ApoJbeta, Apolipoprotein J, CLI, CLU, clusterin, Complement cytolysis inhibitor, Ku70 binding protein 1, KUB1, NA1/NA2, SGP 2, SGP2, SP 40, TRPM 2, TRPM2

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P10909

IMAGES

Immunohistochemistry of paraffin-embedded human liver slide using FNab01782(CLU Antibody) at dilution of 1:50

human blood tissue were subjected to SDS PAGE followed by western blot with FNab01782(CLU antibody) at dilution of 1:1000