anti- CNDP2 antibody

Explore the world of proteolysis and metabolic regulation with our Anti-CNDP2 Antibody, now available in a 100µg size. CNDP2 (Cytosolic Non-specific Dipeptidase 2) is an enzyme involved in the hydrolysis of dipeptides and has implications for amino acid metabolism and peptide degradation.

This meticulously designed antibody offers exceptional specificity and sensitivity, ensuring accurate detection of CNDP2 protein in your experiments. Researchers investigating dipeptidase activity, renal function, or related areas will benefit from the precision and reliability of this antibody.

Our high-quality Anti-CNDP2 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of metabolic research and gain valuable insights into the role of CNDP2 in regulating dipeptide metabolism and its impact on cellular physiology.

Product Name

CNDP2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).

IMMUNOGEN INFORMATION

Immunogen

CNDP dipeptidase 2(metallopeptidase M20 family)

Synonyms

CN2, CPGL, HEL-S-13, PEPA

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q96KP4

IMAGES

PC-3 cells were subjected to SDS PAGE followed by western blot with FNab01795(CNDP2 antibody) at dilution of 1:200