anti- CNOT2 antibody

Delve into the world of gene expression control and RNA metabolism with our Anti-CNOT2 Antibody, available in a 100µg size. CNOT2 (CCR4-NOT Transcription Complex Subunit 2) is a critical component of the CCR4-NOT complex involved in mRNA deadenylation and has implications for mRNA stability and turnover.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring precise detection of CNOT2 protein in your experiments. Researchers investigating post-transcriptional regulation, RNA decay, or related areas will benefit from the precision and reliability of this antibody.

Our high-quality Anti-CNOT2 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of molecular biology research and gain valuable insights into the role of CNOT2 in modulating mRNA dynamics and gene expression.

Product Name

CNOT2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem(ES) cell identity.

IMMUNOGEN INFORMATION

Immunogen

CCR4-NOT transcription complex, subunit 2

Synonyms

CDC36, NOT2

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9NZN8

IMAGES

NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab0180(CNOT2 antibody) at dilution of 1:500