anti- CNOT7 antibody

Unveil the intricacies of RNA degradation and gene expression control with our Anti-CNOT7 Antibody, available in a 100µg size. CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a subunit of the CCR4-NOT complex involved in mRNA deadenylation and has implications for mRNA stability and translation.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring precise detection of CNOT7 protein in your experiments. Researchers investigating post-transcriptional regulation, RNA turnover, or related areas will appreciate the accuracy and reliability of this antibody.

Our high-quality Anti-CNOT7 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Dive into the forefront of molecular biology research and gain valuable insights into the role of CNOT7 in modulating mRNA dynamics and gene expression.

Product Name

CNOT7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

IMMUNOGEN INFORMATION

Immunogen

CCR4-NOT transcription complex, subunit 7

Synonyms

CAF1

Observed MW

33-35 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q9UIV1

IMAGES

IP Result of anti-CNOT7 (IP:FNab01811, 4ug; Detection:FNab01811 1:300) with mouse testis tissue lysate 4800ug.

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab01811(CNOT7 antibody) at dilution of 1:500