anti- Collagen Type I antibody

Venture into the world of tissue resilience and structural support with our Polyclonal Anti-Collagen Type I Antibody, available in a convenient 100µg size. Collagen Type I is a fundamental component of connective tissues, playing a vital role in tissue integrity. With its polyclonal nature, this antibody offers enhanced sensitivity and versatility for your research needs.

This antibody has undergone rigorous quality control measures to ensure specificity and reliability, making it an essential tool for researchers investigating tissue development, wound healing, or the role of collagen I in various diseases. Whether you're conducting Western blotting, immunohistochemistry, or immunoprecipitation experiments, our Polyclonal Anti-Collagen Type I Antibody delivers consistent and reproducible results.

The 100µg size ensures an ample supply of antibody for your experiments, reducing the hassle of frequent reordering. Trust in our Polyclonal Anti-Collagen Type I Antibody to accelerate your scientific exploration of collagen I and its diverse functions in tissue biology.

Product Name

Collagen Type I antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

IMMUNOGEN INFORMATION

Immunogen

collagen, type I, alpha 2

Synonyms

Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4

Observed MW

118 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P08123

IMAGES

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab01836( COL1A2 Antibody) at dilution of 1:100

mouse skin tissue were subjected to SDS PAGE followed by western blot with FNab01836(COL1A2 antibody) at dilution of 1:10