anti- COMMD5 antibody

Journey into the intricate world of cellular regulation and copper metabolism with our Anti-COMMD5 Antibody, thoughtfully developed and conveniently available in a 100µg size. COMMD5 is a protein critical for maintaining copper homeostasis within cells, and it plays a crucial role in cellular copper trafficking.

Our antibody is meticulously designed and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your experiments. Whether you're investigating copper-related disorders, cellular copper transport mechanisms, or the role of COMMD5 in copper homeostasis, this antibody is your dependable research companion.

The 100µg size offers a substantial supply of antibody to support your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COMMD5 Antibody to advance your scientific exploration of copper metabolism and contribute to a deeper understanding of its significance in cellular health.

Product Name

COMMD5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).

IMMUNOGEN INFORMATION

Immunogen

COMM domain containing 5

Observed MW

25-28 kDa

APPLICATION

Tested Application

ELISA, WB, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q9GZQ3

IMAGES

IP Result of anti-COMMD5 (IP:FNab01851, 4ug; Detection:FNab01851 1:500) with mouse heart tissue lysate 3200ug.

mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab01851(COMMD5 antibody) at dilution of 1:1000