anti- COPE antibody

Unlock the mysteries of cellular oxidative stress responses with our Anti-COPE Antibody, thoughtfully developed and available in a convenient 100µg size. COPE, also known as oxidative stress-induced growth inhibitor 1 (OSGIN1), is a protein involved in cellular defense mechanisms against oxidative damage. This high-quality antibody serves as your essential tool for investigating the dynamic processes of oxidative stress response and its implications in cellular health.

Our antibody is meticulously crafted and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your experiments. Whether you're exploring antioxidant pathways, redox signaling, or the role of COPE in diseases associated with oxidative stress, this antibody is your trusted research partner.

The 100µg size offers a generous supply of antibody to support your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COPE Antibody to advance your scientific exploration of oxidative stress responses and contribute to a deeper understanding of cellular resilience.

Unraveling the intricacies of COPE's role in cellular defense mechanisms against oxidative damage is essential for deciphering the complexities of cellular health and its relevance to various diseases. Our antibody empowers you to delve into this intriguing area of research, potentially paving the way for novel therapeutic strategies and improved patient care.

Product Name

COPE antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors(ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity).

IMMUNOGEN INFORMATION

Immunogen

coatomer protein complex, subunit epsilon

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14579

IMAGES

Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using FNab01865(COPE Antibody) at dilution of 1:50

PC-3 cells were subjected to SDS PAGE followed by western blot with FNab01865(COPE antibody) at dilution of 1:500