anti- COPG2 antibody

Step into the realm of intracellular vesicle trafficking with our Anti-COPG2 Antibody, meticulously crafted and available in a convenient 100µg size. COPG2, a subunit of the coatomer protein complex I (COPI), plays a crucial role in maintaining cellular organelle structure and facilitating the transport of proteins within the cell. This high-quality antibody serves as your essential tool for investigating the dynamic processes of intracellular protein sorting.

Our antibody is designed with precision and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're delving into vesicular transport, Golgi function, or the role of COPG2 in diseases such as Golgi-related disorders, this antibody is your dependable research companion.

The 100µg size provides a generous supply of antibody for your experiments, reducing the need for frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COPG2 Antibody to advance your scientific exploration of intracellular protein trafficking and contribute to a deeper understanding of cellular organization.

Unraveling the intricacies of COPG2's role in protein trafficking is essential for deciphering the complexities of cellular organization and its relevance to various diseases. Our antibody empowers you to delve into this fascinating area of research, potentially paving the way for novel therapeutic interventions and improved cellular health.

Product Name

COPG2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors(ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity).

IMMUNOGEN INFORMATION

Immunogen

coatomer protein complex, subunit gamma 2

Observed MW

98 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UBF2

IMAGES

Immunohistochemistry of paraffin-embedded human heart using FNab01867(COPG2 antibody) at dilution of 1:50

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab01867(COPG2 antibody) at dilution of 1:1000