anti- COPZ1 antibody

Explore the intricate world of intracellular protein trafficking with our Anti-COPZ1 Antibody, meticulously crafted and available in a convenient 100µg size. COPZ1, a subunit of the coatomer protein complex I (COPI), is instrumental in maintaining cellular organelle structure and facilitating the transport of proteins within the cell. This high-quality antibody serves as your essential tool for investigating the dynamic processes of intracellular protein sorting.

Our antibody is designed with precision and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're delving into vesicular transport, Golgi function, or the role of COPZ1 in diseases such as Golgi-related disorders, this antibody is your dependable research companion.

The 100µg size provides a substantial supply of antibody for your experiments, reducing the need for frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COPZ1 Antibody to advance your scientific exploration of intracellular protein trafficking and contribute to a deeper understanding of cellular organization.

Unraveling the intricacies of COPZ1's role in protein trafficking is essential for deciphering the complexities of cellular organization and its relevance to various diseases. Our antibody empowers you to delve into this fascinating area of research, potentially paving the way for novel therapeutic interventions and improved cellular health.

Product Name

COPZ1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors(ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

IMMUNOGEN INFORMATION

Immunogen

coatomer protein complex, subunit zeta 1

Synonyms

COPZ

Observed MW

20 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P61923

IMAGES