anti- COTL1 antibody

Embark on a journey into the realm of immune regulation and T-cell biology with our Anti-COTL1 Antibody, meticulously developed and conveniently available in a 100µg size. COTL1, also known as CARMA1, is a critical component of the CARMA1-BCL10-MALT1 (CBM) complex, playing a pivotal role in T-cell receptor signaling and immune response activation. This high-quality polyclonal antibody serves as your essential tool for investigating the intricate processes of immune cell activation and signaling cascades.

Our polyclonal antibody is thoughtfully crafted and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're exploring autoimmune diseases, T-cell signaling, or the role of COTL1 in lymphocyte activation, this antibody is your trusted research partner.

The 100µg size offers a generous supply of antibody to support your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COTL1 Polyclonal Antibody to advance your scientific exploration of immune regulation and contribute to a deeper understanding of T-cell biology.

Unraveling the intricacies of COTL1's role in immune signaling and its impact on autoimmune disorders is essential for deciphering the complexities of immune-mediated diseases and their implications for therapeutic interventions. Our polyclonal antibody empowers you to delve into this intriguing area of research, potentially paving the way for novel immunomodulatory strategies and improved patient care.

Product Name

COTL1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

IMMUNOGEN INFORMATION

Immunogen

coactosin-like 1

Synonyms

CLP

Observed MW

14 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q14019

IMAGES