anti- COX6A1 antibody

Uncover the secrets of mitochondrial function and cellular energy production with our Anti-COX6A1 Antibody, now available in a 100µg size. COX6A1 (Cytochrome C Oxidase Subunit 6A1) is a crucial component of the mitochondrial respiratory chain, playing a pivotal role in oxidative phosphorylation.

This meticulously designed antibody offers exceptional specificity and sensitivity, ensuring accurate detection of COX6A1 protein in your experiments. Researchers investigating mitochondrial biology, energy metabolism, or related areas will benefit from the precision and reliability of this antibody.

Our high-quality Anti-COX6A1 Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Dive into the forefront of cellular bioenergetics research and gain valuable insights into the role of COX6A1 in powering the cell's energy factories.

Product Name

COX6A1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.

IMMUNOGEN INFORMATION

Immunogen

cytochrome c oxidase subunit VIa polypeptide 1

Synonyms

COX6AL

Observed MW

12 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200 - 1:2000; IHC: 1:20 - 1:200

UNIPROT INFORMATION

UniProt ID

P12074

IMAGES