anti- CPEB1 antibody

Unlock the secrets of post-transcriptional gene regulation with our Anti-CPEB1 Antibody. CPEB1, a master regulator of mRNA translation, plays a pivotal role in controlling gene expression in response to synaptic activity and cellular signaling. This 100µg vial of antibody is your gateway to exploring CPEB1's functions in molecular biology and neuroscience.

Our Anti-CPEB1 Antibody is rigorously tested to ensure specificity and sensitivity, making it ideal for various applications, including Western blotting, immunohistochemistry, and RNA immunoprecipitation.

Rely on this antibody to provide consistent and accurate results, empowering you to unravel the intricate mechanisms of mRNA translation regulation and synaptic plasticity. Whether you're investigating neurodevelopmental disorders or synaptic dysfunction, this antibody is an essential tool for your research.

Product Name

CPEB1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element(CPE), an uridine-rich sequence element(consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA; a repression that is relieved by phosphorylation or degradation(By similarity). Involved in the transport of CPE-containing mRNA to dendrites; those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses(By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation(By similarity). Induces the assembly of stress granules in the absence of stress.

IMMUNOGEN INFORMATION

Immunogen

cytoplasmic polyadenylation element binding protein 1

Synonyms

CPEB

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9BZB8

IMAGES