anti- CPNE1 antibody

Dive into the fascinating world of calcium-dependent membrane-binding proteins with our Anti-CPNE1 Antibody, available in a convenient 100µg size. Copine 1 (CPNE1) is a vital member of the CPNE family, contributing to calcium-mediated cellular processes, membrane dynamics, and vesicular trafficking.

This antibody is meticulously designed and rigorously tested for specificity and sensitivity, making it suitable for various applications, including Western blotting, immunoprecipitation, and immunocytochemistry. Whether you are researching neuronal function, synaptic plasticity, or membrane-cytoskeleton interactions, our Anti-CPNE1 Antibody will provide you with precise and reliable results.

Count on this antibody to empower your studies in cell biology, neurobiology, and related fields, as you uncover the molecular mechanisms governing calcium-dependent membrane interactions and cellular processes.

Product Name

CPNE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes(PubMed:14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner(PubMed:14674885). Exhibits calcium-dependent phospholipid binding properties(PubMed:9430674, PubMed:19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner(PubMed:23263657, PubMed:25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner(PubMed:12522145). May function in membrane trafficking(PubMed:9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit(PubMed:18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL(PubMed:18212740).

IMMUNOGEN INFORMATION

Immunogen

copine I

Synonyms

CPN1

APPLICATION

Tested Application

ELISA

UNIPROT INFORMATION

UniProt ID

Q99829