anti- CREM antibody

Embark on a journey into the world of gene regulation and transcriptional control with our Anti-CREM Antibody, available in a convenient 100µg size. CREM (cAMP Response Element Modulator) is a transcription factor that plays a pivotal role in the regulation of gene expression in response to cAMP signaling.

This antibody is meticulously designed and rigorously tested for specificity and sensitivity, making it suitable for various applications, including Western blotting, chromatin immunoprecipitation (ChIP), and immunohistochemistry. Whether you are researching gene regulation, signal transduction pathways, or cellular differentiation, our Anti-CREM Antibody will provide you with accurate and consistent results.

Trust in the accuracy and reliability of this antibody as you advance your research in molecular biology, cell signaling, and related fields. Uncover the molecular mechanisms governing CREM's roles in gene expression control and cellular responses with the assistance of this high-quality antibody.

Product Name

CREM antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation(PubMed:10373550). Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.

IMMUNOGEN INFORMATION

Immunogen

cAMP responsive element modulator

Synonyms

CREM, hCREM 2, ICER, Inducible cAMP early repressor

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q03060

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