anti- CSK antibody

Unlock the secrets of cellular signaling with our Anti-CSK Antibody, now available in a convenient 100µg size. CSK (C-Src Tyrosine Kinase) is a critical player in regulating intracellular signaling pathways, exerting control over cellular responses to a myriad of stimuli.

This meticulously designed antibody has undergone rigorous validation for specificity and sensitivity, making it the ideal choice for a range of applications, including Western blotting, immunoprecipitation, and flow cytometry. Whether you are studying cell proliferation, immune responses, or oncogenesis, our Anti-CSK Antibody will provide you with consistent and reliable results.

Trust in the accuracy and precision of this antibody as you advance your research in cell biology, immunology, and related fields. Explore the intricacies of CSK-mediated signaling pathways and their implications for disease and therapy with the assistance of this high-quality antibody.

Product Name

CSK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases(SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor(TCR) and B-cell receptor(BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

IMMUNOGEN INFORMATION

Immunogen

c-src tyrosine kinase

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P41240

IMAGES