anti- CSPG4,NG2 antibody

Delve into the complex world of proteoglycans and cell surface receptors with our Anti-CSPG4 (NG2) Antibody, now available in a convenient 100µg size. CSPG4 (Chondroitin Sulfate Proteoglycan 4), also known as NG2, is a multifaceted cell surface proteoglycan involved in various cellular processes, including cell adhesion, migration, and signaling.

This expertly crafted antibody is rigorously validated for specificity and sensitivity, making it suitable for various applications, including flow cytometry, immunohistochemistry, and studies of neural development and cancer biology. Whether you are researching neural stem cells, glioblastomas, or the roles of CSPG4 in cell behavior, our Anti-CSPG4 (NG2) Antibody will provide you with accurate and consistent results.

Trust in the accuracy and reliability of this antibody as you advance your research in neuroscience, oncology, and related fields. Uncover the multifaceted roles of CSPG4 in health and disease, and explore its potential as a therapeutic target with the assistance of this trusted antibody.

Product Name

CSPG4,NG2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.

IMMUNOGEN INFORMATION

Immunogen

chondroitin sulfate proteoglycan 4

Synonyms

CSPG4, HMW MAA, MCSP, MCSPG, MEL CSPG, MSK16, NG2

Observed MW

240-250 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q6UVK1

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