anti- CUL3 antibody

The anti-CUL3 antibody, available in a 100µg size, is a versatile tool for researchers delving into the multifaceted functions of Cullin-3 (CUL3) in various cellular processes, particularly its roles in protein ubiquitination and targeted protein degradation.

This polyclonal antibody is meticulously designed to target CUL3 with exceptional specificity and sensitivity, making it ideal for a wide range of applications, including Western blotting, immunohistochemistry, and co-immunoprecipitation assays.

Our anti-CUL3 antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. It is a trusted choice for researchers investigating the molecular mechanisms of protein turnover, cell cycle regulation, and ubiquitin ligase activity.

The 100µg size of this antibody provides researchers with an ample supply for multiple experiments, and it is compatible with various sample types, including cell lysates and tissue sections. Whether studying cell signaling, protein degradation pathways, or ubiquitin-dependent processes, this antibody is an invaluable resource for your research.

Product Name

CUL3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

IMMUNOGEN INFORMATION

Immunogen

cullin 3

Synonyms

KIAA0617

Observed MW

85 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q13618

IMAGES