anti- CX3CL1 antibody

Our Anti-CX3CL1 Antibody, available in a convenient 100µg size, is an essential tool for researchers studying chemokines and their roles in immune responses, inflammation, and cellular adhesion processes.

CX3CL1, also known as fractalkine, is a unique chemokine with complex functions in mediating immune cell adhesion and migration. With our Anti-CX3CL1 Antibody, you can confidently investigate these intricate processes with reliable and consistent results.

We have rigorously validated the specificity and sensitivity of this antibody to ensure accurate and reproducible outcomes in your experiments. Its compact size allows for versatile applications, whether in cell culture assays or in vivo studies. Trust in our Anti-CX3CL1 Antibody to accelerate your scientific investigations and advance your understanding of these critical biological processes.

Product Name

CX3CL1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as a ligand for both CX3CL1 and integrins. Binds to CX3CR1(PubMed:23125415, PubMed:9931005, PubMed:21829356). Binds to integrins ITGAV:ITGB3 and ITGA4:ITGB1. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site(site 1) in integrins. In the absence of CX3CR1, binds to a second site(site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1(PubMed:23125415, PubMed:24789099). The soluble form is chemotactic for T-cells and monocytes and not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium(PubMed:9024663, PubMed:9177350).

IMMUNOGEN INFORMATION

Immunogen

chemokine(C-X3-C motif) ligand 1

Synonyms

FKN, NTT, SCYD1

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P78423

IMAGES