anti- CYP2A6 antibody

Our Anti-CYP2A6 Antibody, available in a 100µg size, is a crucial tool for researchers studying the cytochrome P450 enzyme CYP2A6, responsible for the metabolism of nicotine and several other compounds.

Understanding the functions and genetic variations of CYP2A6 is essential for unraveling its contributions to drug metabolism, tobacco dependence, and the metabolism of procarcinogens. Our antibody has undergone rigorous validation for specificity and sensitivity, ensuring accurate and reproducible results in your experiments.

Its compact size allows for versatility in applications, whether you're conducting enzyme assays, studying nicotine metabolism pathways, or investigating the impact of genetic polymorphisms. Trust in the quality of our Anti-CYP2A6 Antibody to accelerate your scientific investigations and contribute to advancements in pharmacology and addiction research.

Product Name

CYP2A6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 2, subfamily A, polypeptide 6

Synonyms

Coumarin 7 hydroxylase, CPA6, CYP2A, CYP2A3, CYP2A6, CYPIIA6, Cytochrome P450 2A6, Cytochrome P450 IIA3, Cytochrome P450(I), P450C2A, P450PB

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P11509

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