anti- CYP4F11 antibody

Our Anti-CYP4F11 Antibody, provided in a 100µg size, is an indispensable tool for researchers investigating the cytochrome P450 enzyme CYP4F11. This enzyme plays a significant role in the metabolism of endogenous and exogenous compounds, making it a crucial focus of research in the fields of pharmacology, toxicology, and drug development.

CYP4F11 is involved in the oxidation of various substrates, including fatty acids and drugs, contributing to their biotransformation and elimination from the body. Understanding the functions and regulation of CYP4F11 is essential for unraveling its contributions to drug metabolism, lipid homeostasis, and toxicology.

Our antibody has undergone rigorous validation to ensure specificity and sensitivity, enabling accurate and reproducible results in your experiments. Its compact size offers versatility in applications, whether you're conducting drug metabolism studies, investigating the impact of genetic polymorphisms, or exploring potential therapeutic targets.

Trust in the quality of our Anti-CYP4F11 Antibody to advance your research and deepen your understanding of cytochrome P450 enzymes and their roles in drug metabolism and xenobiotic biotransformation.

Product Name

CYP4F11 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1(phylloquinone), and menaquinone-4(MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation(PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate(PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine(PubMed:15364545).

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 4, subfamily F, polypeptide 11

Observed MW

57kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9HBI6

IMAGES