anti- CYP4F8 antibody

Our Anti-CYP4F8 Antibody, available in a 100µg size, is a crucial tool for researchers studying the cytochrome P450 enzyme CYP4F8, known for its role in the metabolism of arachidonic acid and the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE).

CYP4F8 is involved in the conversion of arachidonic acid to 20-HETE, a bioactive lipid with diverse physiological functions, including the regulation of blood pressure, vascular tone, and kidney function. Understanding the functions and regulation of CYP4F8 is essential for unraveling its contributions to lipid signaling pathways and its implications in cardiovascular and renal physiology.

Our antibody has undergone rigorous validation for specificity and sensitivity, ensuring precise and reproducible results in your experiments. Its compact size allows for versatility in applications, whether you're conducting lipid metabolism studies, investigating vascular regulation, or exploring therapeutic targets. Trust in the quality of our Anti-CYP4F8 Antibody to accelerate your scientific investigations and contribute to advancements in cardiovascular and renal research.

Product Name

CYP4F8 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Hydroxylates arachidonic acid(20:4n-6) to(18R)-hydroxyarachidonate. Shows little activity against prostaglandin(PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid(22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid(22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid(22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 4, subfamily F, polypeptide 8

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P98187

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